Staples are less reactive than the least reactive suture. Deeply implanted staples do not affect tissue defenses, although staple cross members that are flush with the skin can produce cross-hatched scarring. The development of disposable staplers with absorbable tacks obviates the need for removal of staples. Subcuticular closure of skin is now also possible through the use of a disposable stapler that uses twin gripper blades to approximate and evert the wound edges and insert a disposable pin into the dermis.