BASIC SCIENCE: Wound Healing

Blood Coagulation
The coagulation cascade starts with the release of the platelet factors (thromboplastins) and other substances from the damaged cells.

Diagram of the Extrinsic Pathway

Diagram of the Intrinsic Pathway

Thromboplastins activate the conversion of prothrombin into thrombin. Thrombin is the enzyme that converts soluble fibrinogen into insoluble fibrin.
Diagram of Fibrin Conversion

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