New Tissue Formation: Collagen Cross-linking
Part of the process of collagen maturation includes developing cross-links between peptide chains or between collagen molecules. It is the cross links that gives collagen and the scar strength. Also during the maturation process, collagenase breaks down inappropriately oriented collagen molecules. The result is that the new collagen, initially laid down in a chaotic, disorganized way, becomes oriented along the lines of contour stress in a manner similar to the way nature intended and nontraumatized collagen appears.